Simultaneous quantitative assessment of morphine tolerance and physical dependence.

Simultaneous Quantitative Assessment of Morphine Tolerance and Physical Dependence. E. LEONG WAY, HORACE H. LOB AND Fu-H5IUNG SHEN 1 Effects of Analgesics and Other Drugs on Mice in Phenylquinone and Rotarod Tests. JACK PEARL, HERBERT STANDER AND DONNA B. MCKEAN 9 Effects of Halothane upon Auditory Recovery Functions in Cats. LUKE M. KITAHATA, Y05HIKUNI AMAKATA AND ROBERT GALAMBOS 14 Effects of d-Amphetamine on Performance under Several Parameters of Multiple Fixed-Ratio, Fixed-Interval Schedules. D. E. MCMILLAN 26 A Central Hypothermic Response to Pilocarpine in the Mouse. MATTHEW J. FRIEDMAN AND JEROME H. JAFFE 34 Central Nervous System Supersensitivity to Pilocarpine after Withdrawal of Chronically Administered Scopolamine. MATTHEW J. FRIEDMAN, JEROME H. JAFFE AND SETH K. SHARPLESS 45 Uptake and Distribution of Some Quaternary Ammonium Compounds in the Central Nervous System of the Rat. J. A. GOSLING AND T. C. LU 56 Intracellular Distribution of C’4-Hemicholinium-3 in the Canine Caudate Nucleus and Hippocampus. OTTO Z. SELLINGER, EDWARD F. DOMINO, VERNON B. HAAR5TAD AND MARGARET E. MOHRMAN 63 Studies on the Metabolism of Diphenyihydantoin in Mice. NIcHoL s GERBER AND KEITH ARNOLD 77 The Metabolism of Tolbutamide in Rat Liver. HUEY G. MCDANIEL, HELEN PODGAINY AND RTJBIN BRES5LER 91 The Action of Phenylmethylsulfonyl Fluoride on Human Acetylcholinesterase, Chymotrypsin and Trypsin. PAOLA TURINI, SHIGERU KUROOKA, MICHAEL STEER, Au o N. CORBASCIO AND THOMAS P. SINGER 98 Studies on the Antifertility Effect and Metabolism of a New, Postcoital Oral Contraceptive, 2-Methyl-3-Ethyl-4-Phenyl-M-Cyclohexene Carboxylic Acid, Sodium Salt. (ORF-4563). ALLAN 5. YARD, LASZLO P. JunAsz AND R. M. GRIMES 105 The Effect of a Saturable Uptake Mechanism on the Slopes of Dose-Response Curves for Sympathomimetic Amines and on the Shifts of Dose-Response Curves Produced by a Competitive Antagonist. S. Z. LANGER AND U. TRENDELENBURG 117 The Effect #{252}f Denervation on the Sensitivity of the Superior Cervical Ganglion of the Pithed Cat. RICHARD D. GREEN, III 143 The Effect of Various Drugs on the Uptake and Metabolism of Tyramine-H’ in the Rat Heart. MICHAEL A. COMMARATO, THEODOREM. BRODY AND JOHN H. MCNEILL.... 151 Temperature Changes Induced by Imidazoline Sympathomimetics in the Rat. PETER LOMAX AND R. S. FOSTER 159 The Effect of Aldosterone on Membrane Potential of Cardiac Muscle Fibers. W. C. DE MELLO AND G. E. MOTTA 166 Sympathomimetic Effects of Acetaldehyde on the Electrical and Contractile Characteristics of Isolated Left Atria of Guinea Pigs. MICHAEL J. WALSH, PHILIP B.